汪香婷, 研究员，博导，美国加州大学圣地亚哥分校分子病理系博士和博士后。主要研究方向为长非编码RNA与疾病，是国际上首批开始长非编码RNA研究的科研人员之一，以第一或（共）通讯作身份在Nature、PLoS Biology、Genome Research、Cell Discovery等国内外高水平期刊上发表了一系列原创性工作。多次受邀为相关领域进展撰写综述文章和在国内外高水平学术会议上做口头报告，承担了RNA Biology杂志副主编、Nature Reviews MCB、Nature Methods和PNAS等期刊审稿人。

主要研究兴趣：

（1）长非编码RNA及其结合蛋白的作用和分子机制

（2）RNA修饰和RNA修饰酶的生物学作用和分子机制

代表性论文（^#共同一作，*通讯作者和共同通讯作者）：

1. Xiaolin Liang^#, Meng Gong^#, Zhikai Wang^#, Jie Wang^#, Weiwei Guo^#, Aoling Cai, Zhenye Yang, Xing Liu, Fuqiang Xu, Wei Xiong*, Chuanhai Fu*, Xiangting Wang*. LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination. Cell Discovery. 2024; 10, 54.

2. Yan Jin, Bowen Zhang, Junxia Lu, Yingdong Song, Wei Wang, Wei Zhang, Fanghong Shao, Meng Gong, Meiting Wang, Xiaolin Liang, Shuqin Li, Zhi Zhang, Ge Shan, Xiangting Wang*. Long non-coding RNA PM maintains cerebellar synaptic integrity and Cbln1 activation via Pax6/Mll1-mediated H3K4me3. PLoS Biology. 2021; 19 (6): e3001297.

3. Tao Shen^#, Wangxiao Xia^#, Sainan Min^#, Zixuan Yang^#, Lehua Cheng^#, Wei Wang, Qianxi Zhan, Fanghong Shao, Xuehan Zhang, Zhiyu Wang, Yan Zhang, Guodong Shen, Huafeng Zhang, Liling Wu, Guangyan Yu, Qingpeng Kong*, Xiangting Wang*. A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression. BMC Biology. 2021; 19 (1), 192.

4. Fei Wang^#, Dalong Ren^#, Xiaolin Liang^#, Shengwei Ke, Bowen Zhang, Bing Hu*, Xiaoyuan Song*, Xiangting Wang*. A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Nucleic Acids Research. 2019; 47(12): 6315-6329.

5. Siling Liu^#, Zhengbo Wang^#, Dong Chen^#, Bowen Zhang^#, Renrong Tian^#, Jing Wu, Ying Zhang, Kaiyu Xu, Liumeng Yang, Chao Cheng, Jian Ma, Longbao Lv, Yongtang Zheng, Xintian Hu, Yi Zhang*, Xiangting Wang*, Jiali Li*. Annotation and cluster analysis of spatiotemporal and sex-related lncRNA expression in Rhesus macaque brain. Genome Research. 2017; 27:1608-1620.

6. Xiangting Wang^#, Xiaoyuan Song^#, Christopher K. Glass, Michael G. Rosenfeld. The long arm of long noncoding RNAs: Roles as sensors regulating gene transcriptional programs. RNA Worlds: From Life's Origins to Diversity in Gene Regulation; 同时发表在Cold Spring Harb Perspect Biol. 2011; 3 (1): a003756.

7. Xiangting Wang, Shigeki Arai, Xiaoyuan Song, Donna Reichart, Kun Du, Gabriel Pascual, Paul Tempst, Michael G. Rosenfeld*, Christopher K. Glass*, Riki Kurokawa*. Induced ncRNAs allosterically modify RNA-binding Proteins in cis to inhibit transcription. Nature. 2008; 454 (7200):126-130.

招生招聘：

实验室长期招聘博士后、硕博研究生和本科实习生，欢迎对RNA研究有兴趣者或具有交叉学科经验的人员与我们联系。

联系方式：

Tel: 86-551-63600079

e-mail: wangxt11@ustc.edu.cn

homepage: https://wangxt-lab.ustc.edu.cn/main.htm