博士、博士生导师、副教授
出生于安徽省。1989年至1993年就读于安徽师范大学生命科学学院获学士学位。1993年至1996年就读于北京师范大学生命科学学院，获硕士学位，2000年至2003年就读于日本京都大学，获博士学位。1996-2003年在北京师范大学生命科学学院工作，2003年至2006年在京都大学和石川县立大学作博士后研究，2006年至2008年在美国弗吉尼亚理工大学作博士后研究。2008年4月作为中国科技大学优秀人才引进，现为生命科学学院副教授。2009年2-6月，在美国休斯敦大学学习基于芯片的高通量DNA合成技术。共在Nucleic Acid Research, Metabolic Engineering, Bioresource Technology, Microbial Cell Factories等SCI学术期刊发表研究论文30余篇。
主要研究兴趣：
1. 基于微流芯片的高保真高通量基因合成。采用通过芯片合成的寡核苷酸为出发材料，通过高通量的扩增、纠错及组装降低DNA合成成本，提高合成效率。
2. 利用生物质生产各种化学品的耐热工程酵母的构建。利用木质纤维素生物质以及菊芋为材料生产乙醇、木糖醇、丙酮酸、乳酸、果糖等有较高附加值的产品。
3. 重组蛋白高温表达体系的构建。在耐热酵母及耐热丝状真菌中构建重组蛋白的表达系统。
代表性论文：
1. Zhang Kehui, Jiang Ziyun, Li Xingjiang, Wang Dongmei, Hong Jiong* (2024). Enhancing simultaneous saccharification and co-fermentation of corncob by Kluyveromyces marxianus through overexpression of putative transcription regulator. Bioresource Technology, 399, 130627
2. Hu Shenglin, Xu Li*, Xie Canglin, Hong Jiong*, (2024). Structural Insights into the Catalytic Activity of Cyclobacterium marinum N-Acetylglucosamine Deacetylase. Journal of Agricultural and Food Chemistry 72, 783–793.
3. Zhang Nini, Wang Feier, Nwamba, Marknoah Chinenye, Wang Dongmei*, Hong Jiong*, (2023). Enhancing tolerance of Kluyveromyces marxianus to lignocellulose-derived inhibitors and its ethanol production from corn cob via overexpression of a nitroreductase gene. Industrial Crops & Products, 203, 117136
4. Yang Xiaoxue,Wang Dongmei, Hong Jiong*. (2022). Carotenoid production from nondetoxified xylose mother liquid or corncob hydrolysate with engineered Kluyveromyces marxianus. Bioresource Technology, 364, 12808
5. Hua Yan, Wang Jichao, Zhu Yelin, Zhang Biao, Kong Xin, Li Wenjie, Wang Dongmei, Hong Jiong*, (2019). Release of glucose repression on xylose utilization in Kluyveromyces marxianus to enhance glucose-xylose co-utilization and xylitol production from corncob hydrolysate. Microbial Cell Factories. 18：24.
6. Kong Xin, Zhang Biao, Hua Yan, Zhu Yelin, Li Wenjie, Wang Dongmei, HongJiong*, (2019). Efficient L-lactic acid production from corncob residue using metabolically engineered thermo-tolerant yeast. Bioresource Technology. 273， p220-230
7. Zhang Biao, Zhu Yelin, Zhang Jia, Wang Dongmei, Sun Lianhong, Hong Jiong* , (2017). Engineered Kluyveromyces marxianus for pyruvate production at elevated temperature with simultaneous consumption of xylose and glucose. Bioresoure Technology, 224, 553-562.
8. Zhang Biao, Zhang Jia, Wang Dongmei, Han Ruixiang., Ding Rui, Gao Xiaolian., Sun Lianhong, Hong Jiong*, (2016). Simultaneous fermentation of glucose and xylose at elevated temperatures co-produces ethanol and xylitol through overexpression of a xylose-specific transporter in engineered Kluyveromyces marxianus. Bioresource Technology, 216, 227-237. （Best article in this issue)
9. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Sun Lianhong and Hong Jiong*, (2015). Rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase-xylitol dehydrogenase pathway. Metabolic Engineering, 31, 140-152.
10. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian and Hong Jiong*, (2015). Improving xylitol production at elevated temperature with engineered Kluyveromyces marxianus through over-expressing transporters. Bioresource Technology 175: 642-645.
11. Wan, Wen; Li, Lulu; Xu, Qianqian; Wang, Zhefan; Yao, Yuan; Wang, Rongliang; Zhang, Jia; Liu, Haiyan; Gao, Xiaolian*; Hong, Jiong* (2014). Error removal in microchip-synthesized DNA using immobilized MutS. Nucleic Acids Research, 42(12), e102
12. Zhang Jia, Zhang Biao, Wang Dongmei, Gao Xiaolian, Hong Jiong* (2014). Xylitol production at high temperature by engineered Kluyveromyces marxianus. Bioresource Technology152:192-201.
更多文章：
https://faculty.ustc.edu.cn/hongjiong/en/zdylm/5760/list/index.htm
联系方式：
邮箱：hjiong@ustc.edu.cn 联系电话：0551-63600705.
网页：http://synbio.ustc.edu.cn/高晓连教授实验室
research ID：http://www.researcherid.com/rid/N-1996-2013