主要研究兴趣：

1. NK细胞免疫治疗相关卡控点的发现

2. NK细胞抑制性受体与肿瘤微环境的相关性研究

孙昊昱，中国科学技术大学生命科学与医学部副教授。2010年获得多伦多大学理学荣誉学士。2016年获得中国科学技术大学细胞生物学博士。同年在中国科学院天然免疫与慢性疾病重点实验室做博士后，于2020年转聘为副教授。主要从事NK细胞免疫治疗相关卡控点的发现以及其与肝癌肿瘤微环境的相关性研究，获得国家自然科学基金委面上项目和青年基金项目各一项，参与（骨干）科技部重点研发计划一项。主要工作以第一作者和/或通讯作者发表于Hepatology、Cancer Immunology Research、Cancer Research、Cellular & Molecular Immunology等学术期刊。

主要代表论文：

1. Sun H, Huang Q, Huang M, Wen H, Lin R, Zheng M, Qu K, Li K, Wei H, Xiao W, Sun R, Tian Z*, Sun C*. Human CD96 Correlates to Natural Killer Cell Exhaustion and Predicts the Prognosis of Human Hepatocellular Carcinoma. Hepatology. 2019;70(1):168-83.

2. Sun H*, Liu L, Huang Q, Liu H, Huang M, Wang J, Wen H, Lin R, Qu K, Li K, Wei H, Xiao W, Sun R, Tian Z*, Sun C*. Accumulation of Tumor-Infiltrating CD49a(+) NK Cells Correlates with Poor Prognosis for Human Hepatocellular Carcinoma. Cancer Immunol Res. 2019;7(9):1535-46.

3. Sun H, Xu J, Huang Q, Huang M, Li K, Qu K, Wen H, Lin R, Zheng M, Wei H, Xiao W, Sun R, Tian Z*, Sun C*. Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC. Cancer Res. 2018;78(23):6581-93.

4. Sun H*, Sun C, Xiao W, Sun R. Tissue-resident lymphocytes: from adaptive to innate immunity. Cell Mol Immunol. 2019;16(3):205-15.

5. Sun H*, Sun C*. The Rise of NK Cell Checkpoints as Promising Therapeutic Targets in Cancer Immunotherapy. Front Immunol. 2019;10:2354.

6. Sun H, Song J, Weng C, Xu J, Huang M, Huang Q, Sun R, Xiao W*, Sun C*. Association of decreased expression of the macrophage scavenger receptor MARCO with tumor progression and poor prognosis in human hepatocellular carcinoma. J Gastroenterol Hepatol. 2017;32(5):1107-14.

7. Sun H, Xu J, Huang M, Huang Q, Sun R, Xiao W*, Sun C*. CD200R, a co-inhibitory receptor on immune cells, predicts the prognosis of human hepatocellular carcinoma. Immunology letters. 2016;178:105-13.