教授，主任医师，博士生导师。现任中国科学技术大学临床医学院和附属第一医院副院长、南京大学神经病学研究所所长。

致力于神经病学、脑血管病和介入诊疗临床、教学与研究30余年。入选国家百千万人才工程、全国优秀科技工作者和军队杰出专业技术人才奖。享受国务院政府特殊津贴。荣立二等功2次。

 以第一完成人获得国家科技进步二等奖1项、省部级科技进步一等奖共5项。以第一或通讯作者在New England Journal of Medicine、Lancet、Lancet Neurology、Journal of Clinical Investigation、Nature Communications、Neurology、Stroke等期刊发表SCI论文300余篇。获国家专利10余项。负责国家自然基金重点和重大国际合作项目、国家重点研发计划专项及省部级以上各类科研基金30余项。牵头制定了中国脑血管病介入诊断与治疗相关指南或专家共识14部。

 担任中国研究型医院学会介入神经病学专业委员会主任委员、中国医师协会神经内科医师分会常委、神经介入专委会主委和中华医学会神经病学分会神经血管介入协作组组长等学术职务。

一、主要研究方向（招生专业）及内容：

临床医学、神经病学

1、脑血管病介入诊断与治疗；

2、脑血管病人工智能辅助诊断与临床预后；

3、神经系统疾病转化医学研究。

二、代表性论文：

1. Tao C, Nogueira RG#, Zhu Y#, Sun J, Han H#, Yuan G, Wen C, Zhou P, Chen W, Zeng G, Li Y, Ma Z, Yu C, Su J, Zhou Z, Chen Z, Liao G, Sun Y, Ren Y, Zhang H, Chen J, Yue X, Xiao G, Wang L, Liu R, Liu W, Liu Y, Wang L, Zhang C, Liu T, Song J, Li R, Xu P, Yin Y, Wang G, Baxter B, Qureshi AI, Liu X*, Hu W*; ATTENTIONInvestigators. Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion. N Engl J Med. 2022 Oct 13;387(15):1361-1372.   IF 176.079

2. Liu X*, Dai Q, Ye R, Zi W, Liu Y, Wang H, Zhu W, Ma M, Yin Q, Li M, Fan X, Sun W, Han Y, Lv Q, Liu R, Yang D, Shi Z, Zheng D, Deng X, Wan Y, Wang Z, Geng Y, Chen X, Zhou Z, Liao G, Jin P, Liu Y, Liu X, Zhang M, Zhou F, Shi H, Zhang Y, Guo F, Yin C, Niu G, Zhang M, Cai X, Zhu Q, Chen Z, Liang Y, Li B, Lin M, Wang W, Xu H, Fu X, Liu W, Tian X, Gong Z, Shi H, Wang C, Lv P, Tao Z, Zhu L, Yang S, Hu W, Jiang P, Liebeskind DS, Pereira VM, Leung T, Yan B, Davis S, Xu G, Nogueira RG*; BEST Trial Investigators. Investigators† Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial. Lancet Neurology. 2020 Feb;19(2):115-122.   IF 59.935

3. Xie Y, Zhang X#, Xu P#, Zhao N, Zhao Y, Li Y, Hong Y, Peng M, Yuan K, Wan T, Sun R, Chen D, Xu L, Chen J, Guo H, Shan W, Li J, Li R, Xiong Y, Liu D, Wang Y, Liu G, Ye R*, Liu X*. Aberrant oligodendroglial LDL receptor orchestrates demyelination in chronic cerebral ischemia. J Clin Invest. 2021 Jan 4;131(1):e128114. doi: 10.1172/JCI128114.   IF 19.456

4. Zhao Y#, Zhu W#, Wan T#, Zhang X, Li Y, Huang Z, Xu P, Huang K, Ye R*, Xie Y*, Liu X*. Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice. Nat Commun. 2022 Nov 10;13(1):6813.    IF 17.694

5. Wan T, Zhu W#, Zhao Y#, Zhang X, Ye R, Zuo M, Xu P, Huang Z, Zhang C, Xie Y*, Liu X*. Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice. Nat Commun. 2022 Mar 3;13(1):1134.    IF 17.694

6. Liu R, Yin Q, Li M, Ye R, Zhu W, Liu X*. Diagnosis and treatment evaluation of in-stent restenosis of carotid artery stenting using optical coherence tomography. Neurology. 2019 Jan 8;92(2):99-100.   IF 11.8

7. Wang J, Li F, Xiao L, Peng F, Sun W*, Li M, Liu D, Jiang Y, Guo R, Li H, Zhu W, Xu G, Liu X*. Depressed TSH level as a predictor of poststroke fatigue in patients with acute ischemic stroke.Neurology. 2018 Nov 20;91(21):e1971-e1978.   IF 11.8

8. Xiao L, Ma M#, Gu M, Han Y, Wang H, Zi W, Yang D, Hao Y, Lv Q, Ye R, Sun W*, Zhu W, Xu G, Liu X*; ACTUAL Investigators. Renal impairment on clinical outcomes following endovascular recanalization. Neurology. 2020 Feb 4;94(5):e464-e473.   IF 11.8

9. Dai Q, Sun W#, Xiong Y, Hankey GJ, Xiao L, Zhu W, Ma M, Liu W, Liu D, Cai Q, Han Y, Duan L, Chen X, Xu G, Liu X*. From clinical to tissue-based dual TIA: Validation and refinement of ABCD3-I score. Neurology. 2015 Apr 7;84(14):1426-32.   IF 11.8

10. Yuan K, Chen J, Xu P, Zhang X, Gong X, Wu M, Xie Y, Wang H, Xu G, Liu X*. A Nomogram for Predicting Stroke Recurrence Among Young Adults. Stroke. 2020 Jun;51(6):1865-1867.   IF 10.17

11. Xiao L, Lan W, Sun W, Dai Q, Xiong Y, Li L, Zhou Y, Zheng P, Fan W, Ma N, Guo Z, Chen X, Xie X, Xu L, Zhu W*, Xu G, Liu X*. Chronic Kidney Disease in Patients With Lacunar Stroke: Association With Enlarged Perivascular Spaces and Total Magnetic Resonance Imaging Burden of Cerebral Small Vessel Disease. Stroke. 2015 Aug;46(8):2081-6.   IF 10.17

三、在研项目(仅限于主要负责人)