中国科学技术大学生命科学与医学部特任教授，博士生导师。2021年毕业于中国科学技术大学神经生物学系（导师： 熊伟），2021-2025年于中国科学技术大学从事博士后研究（合作导师：占成），2025年入选国家青年人才计划，2026年1月至今任中国科学技术大学特任教授。

长期从事昼夜节律与神经-免疫互作开展基础及临床转化研究，重点聚焦于基因造血干细胞移植、移植物抗宿主病等临床关键难题，系统性揭示时间节律、神经调控与炎症免疫微环境的内在关联，为突破重大疾病防治瓶颈提供了全新理论范式与干预策略。研究成果发表于Cell、Science Advances、Nature Communications等期刊，相关成果获“中国血液学十大进展”。

代表性论文列表：

1. Yiwen Hou^†, Yue Wu^†, Yang Cao^†, Xiaoxia Hu^†, Yuqian Sun^†, Hongmei Wang^†, Liang Wang, Jialin Zhou, Zhonglin Zhang, Zhiwei Liu, Baolin Tang, Kaidi Song, Guangyu Sun, Wen Gao, Tianqi Zheng, Ping Wu, Weiwei Wu, Dapeng Ju, Xiaoyu Zhu*, Cheng Zhan*. Optimizing Stem Cell Infusion Timing in the Prevention of Acute Graft versus Host Disease. Cell, 188, 3030-3044.e3017 (2025).

2. Yiwen Hou^†; Guichang Zou^†; Xianglian Wang; Hui Guo; Xiao Ma; Xingyu Cheng; Zhiyong Xie; Xin Zuo; Jing Xia; Huanhuan Mao; Man Yuan; Qi Chen; Peng Cao; Yupeng Yang; Li Zhang; Wei Xiong*. Coordinated activity of a central pathway drives associative opioid analgesic tolerance.Science Advances,9: eabo5627 (2023)

3. Yue Wu^†;Yiwen Hou^†; Dongyao Wang; Liang Wang; Kaidi Song; Guangyu Sun; Aijie Huang;Meijuan Tu; Lu Huang; Jialin Zhou; Weiwei Wu; Baolin Tang; Cheng Zhan; Xiaoyu Zhu; Circadian fluctuation of soluble CD26 dictates the impact of the timing of cord blood transplantation on acute graft-versus-host disease, Nature Communications, 2026

4.  Xiaoqun Wang^†;Yiwen Hou^†; Zhuanghao Hou; Wei Xiong*; Guangming Huang*. Mass Spectrometry Imaging of Brain Cholesterol and Metabolites with Trifluoroacetic Acid-Enhanced Desorption Electrospray Ionization. Analytical Chemistry, 91(4): 2719~2726 (2019)

5. Xu S^†, Zhang R, Jin S, Luo H,Hou Y, He S, Shi Z, Zhao R, Chen Z, Wang B, Chen C, Xue Q, Sun M, Fang S, Zou G, Xiong W, Zhang Y. The activation of catecholamine neurons in the rostral ventrolateral medulla drives ventricular remodeling after myocardial ischemia/reperfusion injury. Basic Res Cardiol. 2025 Oct;120(5):835-854.

6. Hongying Zhu^†; Ning Wang^†; Lei Yao; Qi Chen; Ran Zhang; Junchao Qian;Yiwen Hou;Weiwei Guo; Sijia Fan; Siling Liu; Qiaoyun Zhao; Feng Du; Xin Zuo; Yujun Guo; Yan Xu; Jiali Li; Tian Xue; Kai Zhong; Xiaoyuan Song; Guangming Huang*; Wei Xiong*. Moderate UV exposure enhances learning and memory by promoting a novel glutamate biosynthetic pathway in the brain. Cell, 173, 1716-1727 (2018)

   
   

招生招聘：

本课题组长期招聘神经生物学和免疫学等相关背景的博士后、技术员和科研助理。

同时热忱欢迎对本实验室研究方向感兴趣的本科生前来攻读硕士、博士学位。

联系方式：hyw1992@ustc.edu.cn