王育才

王育才

2022-01-08来源:生命科学学院



教授,博士生导师。国家杰出青年基金获得者(2020年),国家青年高层次海外人才计划入选者(2015年)。2005年于中国科学技术大学获得学士学位;2010年于中国科学技术大学获得博士学位;20111月起先后于圣路易斯华盛顿大学生物医学工程系、佐治亚理工学院生物医学工程系及芝加哥大学James Franck研究所从事博士后研究。20159月入职中国科学技术大学生命科学学院任教,主持或参与基金委国际合作与交流项目、重大研究计划集成项目、重点项目、面上项目;科技部重点研发“纳米专项”、科技部重点研发“变革性项目”;中国科学院基础与交叉前沿科研先导专项等。多年来一直从事纳米材料在癌症治疗及其体内生物界面的研究,在Nat. Nanotech.Nat. Mater.Nat. Biomed. Eng.Nat. Commun.国际学术期刊发表研究论文100余篇。


研究方向:生物医用高分子、核酸药物、显微活体成像


代表性论文(#为第一作者,*为通讯作者):    

[1]   W. Jiang,# Z. Guo,# Q. Wang,#,* Z. Chen, W. Dong, Q. Liang, Y. Hao, H. Pan, C. Zeng, H. Liu* and Y.C. Wang*. Enhanced nanoparticle delivery across vascular basement membranes of tumours using nitric oxide.. Nature Biomedical Engineering, 2025, doi:10.1038/s41551-025-01385-w.

[2]   Y. Liu,# Q. Liu,# B. Zhang,# S. Chen, Y. Shen, Z. Li, J. Zhang, Y. Yang, M. Li* and Y.C. Wang*. Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PD-L1 within lipid nanoparticles. Nature Biomedical Engineering, 2025, doi: 10.1038/s41551-025-01373-0.

[3]      W. Dong#, Z. B. Li#, T. L. Hou#, Y. Q. Shen, Z. X. Guo, Y. T. Su, Z. Q. Chen, H. M. Pan, W. Jiang*, and Y. C. Wang*. Multicomponent Synthesis of Imidazole-Based Ionizable Lipids for Highly Efficient and Spleen-Selective Messenger RNA Delivery. J. Am. Chem. Soc.,2024, 146, 22, 15085–15095.

[4]      M. Luo#, Q. Wang#, G. Zhao#, W. Jiang, C. C. Zeng, Q. A. Zhang, R. Y. Yang, W. Dong, Y. X. Zhao, G. Z. Zhang, J. Jiang, Y. C. Wang*, Q. Zhu*. Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing. National Science Review, 2024, 11, nwad269.

[5]      Q. Wang#, Q. R Liang#, J.X. Dou, H. Zhou, C. C. Zeng, H. M. Pan, Y. Q. Shen, Q. L., Y. Liu, D. T. Leong*, W. Jiang*, Y. C. Wang*. Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumors. Nature Nanotechnology,2024, 19, 95-105.

[6]      M. I. Setyawati #*, Q. Wang #, N. Ni, J. K. Tee, K. Ariga, P. C. Ke, H. K. Ho, Y. C. Wang*, D. T. Leong*. Engineering tumoral vascular leakiness with gold nanoparticles. Nature Communications, 2023, 14, 1, 4269.

[7]      G. Zhang #, Q. Wang #, W. Tao #, W. Jiang, E. Eran, Y. C. Wang*, S. Zhu *. Glucosylated nanoparticles for the oral delivery of antibiotics to the proximal small intestine protect mice from gut dysbiosis. Nature Biomedical Engineering. 2022, 6, 7, 867-881.

[8]      Y. Wu#, Y. Shen #, N. Wu #, X. Zhang #, S. Chen, C. Yang, J. Zhou, Y. Wu, D. Chen, L. Wang, Y. Wang, J. Xu, K. Liu, C. Wang, H. Zhang *, N. Xia *, S. Chiu *, Y. C. Wang*. Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates, Cell Research 2022, 32, 10, 949-952.

[9]      M. Li#, S. Li#, H. Zhou, X Tang, Y. Wu, W. Jiang, Z. Tian, X. Zhou, X. Yang, Y. C. Wang*. Chemotaxis-Driven Delivery of Nano-pathogenoids for Complete Eradication of Tumors Postphototherapy. Nature Communications, 2020, 11, 1, 1126.

[10]   P. Chen#, Y. Ma#, Z. Zheng#, C. Wu, Y. C. Wang*, G. L. Liang*. Facile Syntheses of Conjugated Polymers for Photothermal Tumour Therapy. Nature Communications, 2019, 10, 1, 1192.

 

 


上一篇:下一篇: