博士生导师、中国科学技术大学生命科学与医学部特任研究员

中国科学技术大学附属第一医院神经内科副主任医师,行政副主任。

中国医师协会神经介入专委会委员/秘书长

中国研究型医院介入神经病学专业委员会委员

安徽省医学会神经病学分会青委会副主委

一、学习及工作经历

2003--2008年，徐州医学院，本科，学士，临床医学专业；

2008--2011年，南京大学医学院，硕士，神经病学专业；

2011--2014年，南方医科大学第一临床学院，博士，神经病学专业；

2014--2018年，南京军区南京总医院（东部战区总医院），神经内科，主治医师，南京大学神经病学研究所脑血管病临床研究方向PI；

2019年--至今，中国科学技术大学附属第一医院，神经内科，副主任医师；

二、学术成果及影响

致力于神经病学尤其是脑血管病相关临床研究多年，主持国家自然科学基金，安徽省自然科学基金等7项基金项目，获省部级科技进步奖三项，安徽省卫生健康骨干人才。在Radiology, JCSM，Neurology等期刊发表研究论文40余篇。

在教育教学方面主持医学科研设计课程，获省级课程项目一项。培养硕士博士研究生十余名，多人获国家奖学金，中国科学技术大学优秀毕业生等。

三、在研项目(仅限于主要负责人)

四、主要研究方向（招生专业）及内容

临床医学/神经病学

1） 脑血管病血管内介入治疗技术的临床应用

2）卒中后非运动障碍的功能及影像学研究

3）基于大数据的心脑疾病公共卫生研究

五、代表性论文（近五年）

1. Sun W, Zhang P, Hu M, Zhong J, Zhang W, Dong Y, Chao X, Huang H, Wen J, Xiao L, Xu Y. Endovascular Thrombectomy for Acute Vertebrobasilar Artery Occlusion with Mild Deficits: A Multicenter Registry Study. Radiology. 2024. In press.

2. Zhang P, Zhong J, Liu X, Sun W*. The association between dynamic changes in vitamin D and frailty alterations: A prospective analysis of UK Biobank participants. J Cachexia Sarcopenia Muscle. 2024 Oct;15(5):1722-1732. doi: 10.1002/jcsm.13525. Epub 2024 24.

3. Zhang W, Duan C, Niu M, Zhu B, Zhong J, Xu Y, Xiao L, Li Q, Liu X, Sun W*. Endovascular treatment in pediatric stroke: an individual patient pooled analysis on presentation, management and outcomes. J Neurointerv Surg. 2024 8:jnis-2024-022277.

4. Lu Y, Wu Z, Wang Z, Zhang P, Zhang F, Hu M, Lan W, Liang Y, Yi J, Sun W*. Rescue stenting after failure of endovascular thrombectomy for acute vertebrobasilar artery occlusion: data from the PERSIST registry. J Neurointerv Surg. 2024 14;16(4):347-351. (IF=4.5/Q1)

5. Zhong J, Zhang P, Dong Y, Xu Y, Huang H, Ye R, Liu X, Sun W*. Well-Being and Cardiovascular Health: Insights From the UK Biobank Study. J Am Heart Assoc. 2024;13(19):e035225.

6. Zhang W, Duan C, Niu M, Zhang P, Xu Y, Xiao L, Li Q, Liu X, Sun W*. Sex Differences in Prognosis of Childhood Arterial Ischemic Stroke: Results From Chinese Pediatric Ischemic Stroke Registry Multicenter Registry. Pediatr Neurol. 2024 Jun;155:193-199

7. Zhang P, Zhang Z, Zhong J, Zheng X, Zhou J, Sun W*. Cardiovascular diseases consequences of type 1, type 2 diabetes mellitus and glycemic traits: A Mendelian randomization study. Diabetes Res Clin Pract. 2024;208:111094

8. Chao X, Fang Y, Lu Z, Wang J, Yin D, Shi R, Wang P, Liu X, Sun W*. Impairments of neurovascular coupling after stroke lower glymphatic system function and lead to depressive symptom: A longitudinal cohort study. J Affect Disord. 2024 Sep 3;367:255-262.

9. Chao X, Wang J, Dong Y, Fang Y, Yin D, Wen J, Wang P, Sun W*. Neuroimaging of neuropsychological disturbances following ischaemic stroke (CONNECT): a prospective cohort study protocol. BMJ Open. 2024 29;14(1):e077799.

10. Zhang P, Xu P, Duan Z, Zhang F, Fang Y, Yan D, Zhang H, Cai Q, Huang X, Huang Z, Gu M, Xiao L, Wang J, Sun W*; PERSIST Investigators. Effects of admission systemic inflammatory indicators on clinical outcomes in patients with vertebrobasilar artery occlusion: insight from the PERSIST registry. J Neurointerv Surg. 2023;15(e2):e270-e276

11. Xu Y, Zhang P, Li W, Wang J, Xiao L, Huang X, Duan Z, Li Y, Peng F, Zhang F, Luo G, Sun W*. Temporal progression of functional independence after mechanical thrombectomy in acute vertebrobasilar artery occlusions. J Neurointerv Surg. 2023 18:jnis-2023-020939.

12. Zhong J, Cai H, Zhang Z, Wang J, Xiao L, Zhang P, Xu Y, Tu W, Zhu W, Liu X, Sun W*. Serum uric acid and prognosis of ischemic stroke: Cohort study, meta-analysis and Mendelian randomization study. Eur Stroke J. 2024;9(1):235-243.

13. Zhang P, Li H, Wang J, Zhang F, Xiao L, Fang Y, Yan D, Xu G, Liu C, Huang Z, Gu M, Zhang H, Sun W*. Sex differences in outcomes after endovascular treatment of patients with vertebrobasilar artery occlusion. Eur Stroke J. 2023 Jun;8(2):566-574.

14. Zhang F, Huang Z, Lu W, Wang Z, Lu Y, Wang M, Zhang P, Hu M, Xiao L, Liu X, Sun W*. CT-based and CTA-based posterior circulation ASPECTS in acute basilar artery occlusion: An Agreement Study. Cerebrovasc Dis. 2023, in press.

15. Xu Y, Huang Z, Zhang P, Zhong J, Zhang W, Hu M, Huang X, Wu Z, Xu G, Zhang M, Sun W*. Effect of INR on Outcomes of Endovascular Treatment for Acute Vertebrobasilar Artery Occlusion. Transl Stroke Res. 2024;53(3):239-244.

16. Gu M, Wang J, Xiao L, Chen X, Wang M, Huang Q, Zhou J, Sun W*. Malnutrition and poststroke depression in patients with ischemic stroke. J Affect Disord. 2023 Aug 1;334:113-120.

17. Huang X, Chen C, Li M, Duan Z, Ji Y, Wu K, Xu J, Xiao L, Xu P, Sun W*. First-pass effect in patients with acute vertebrobasilar artery occlusion undergoing thrombectomy: insights from the PERSIST registry. Ther Adv Neurol Disord. 2022 Nov 26;15:17562864221139595.

18. Sun W*, Duan Z, Xu P, Xiao L, Wang J, Gui W, Luo G, Wu Z, Han Z, Li W, Xu G, Liu F, Yi J, Liu C, Zhang Y, Liu H. The safety and effectiveness of endovascular treatment for patients with vertebrobasilar artery occlusions: according to the BEST and BASICS criteria. Ther Adv Neurol Disord. 2022 Aug 13;15:17562864221114627.

19. Xu P, Hong Y, Xie Y, Yuan K, Li J, Sun R, Zhang X, Shi X, Li R, Wu J, Liu X, Hu W, Sun W*. TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage. Transl Stroke Res. 2021 Aug;12(4):643-659.

20. Tao C, Gu M, Xu P, Wang J, Xiao L, Gui W, Li F, Jiang S, Liu X, Hu W, Sun W*. Stressful life events can predict post-stroke fatigue in patients with ischemic stroke. Eur J Neurol. 2021 Sep;28(9):3080-3088.

21. Xiao L#; Ma M#; Gu M; Han Y; Wang H, Zi W; Yang D; Hao Y; Lv Q; Ye R; Sun W*; Zhu W; Xu G, Liu X*, on behalf of the ACTUAL Investigators. Renal impairment on clinical outcomes following endovascular recanalization. Neurology. 2020 4;94(5):e464-e473.

六、联系方式

E-mail: sunwen_neuro@fsyy.ustc.edu.cn  

电话：0551-62284314