孙军，特任研究员，博士生导师。2012年本科毕业于南开大学，2018年博士毕业于中国科学院上海生物化学与细胞生物学研究所(现中国科学院分子细胞科学卓越创新中心)，同年进入康奈尔大学进行博士后研究，将于2024年9月加入中国科学技术大学生命科学与医学部。主要研究骨骼干细胞的鉴定，探索干细胞功能失调如何导致骨骼疾病的发生，相关工作以第一作者身份发表于Nature，Nature Communications, Science Advances等杂志上。荣获美国骨研促进会（AIMM）John Haddad青年学者奖，美国骨代谢学会（ASBMR）青年学者奖，国际华人骨研会（ICMRS）Webster Jee青年学者奖，美国儿童肿瘤基金（CTF）青年学者奖等。
研究兴趣：新型骨骼干细胞的鉴定及功能研究；骨骼干细胞在脊柱疾病发生过程中的作用；癌症骨转移的调控机制；干细胞介导的骨损伤修复和再生。
招生招聘：
课题组长期招聘对骨骼干细胞，骨骼疾病及癌症骨转移等方向感兴趣的博士后、特任副研究员。同时诚挚欢迎对本课题组感兴趣的同学加入课题组，攻读学位。
代表性论文(*共同一作，#共同通讯作者)：
1. Sun J, Hu L, Bok S, Yallowitz AR, Cung M, McCormick J, Zheng LJ, Debnath S, Niu Y, Tan AY, Lalani S, Morse KW, Shinn D, Pajak A, Hammad M, Suhardi VJ, Li Z, Li N, Wang L, Zou W, Mittal V, Bostrom MPG, Xu R, Iyer S, Greenblatt MB. A vertebral skeletal stem cell lineage driving metastasis. Nature. 2023 Sep;621(7979):602-609.
2. Sun J*, Shin DY*, Eiseman M, Yallowitz AR, Li N, Lalani S, Li Z, Cung M, Bok S, Debnath S, Marquez SJ, White TE, Khan AG, Lorenz IC, Shim JH, Lee FS, Xu R#, Greenblatt MB#. SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts. Nat Commun. 2021 Jul 29;12(1):4611.
3. Sun J*, Feng H*, Xing W, Han Y, Suo J, Yallowitz AR, Qian N, Shi Y, Greenblatt MB, Zou W. Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing. Sci Adv. 2020 Nov;6(45).
4. Sun J, Ermann J, Niu N, Yan G, Yang Y, Shi Y, Zou W. Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts. Bone Res. 2018;6:14.
5. Sun J, Greenblatt MB. To the bones: mapping the skeletal LEPR(+) pool to component cell types. EMBO J. 2022 Feb 15;41(4):e110343. doi: 10.15252/embj.2021110343.
6. Bok S, Yallowitz AR, Sun J, McCormick J, Cung M, Hu L, Lalani S, Li Z, Sosa BR, Baumgartner T, Byrne P, Zhang T, Morse KW, Mohamed FF, Ge C, Franceschi RT, Cowling RT, Greenberg BH, Pisapia DJ, Imahiyerobo TA, Lakhani S, Ross ME, Hoffman CE, Debnath S#, Greenblatt MB#. A multi-stem cell basis for craniosynostosis and calvarial mineralization. Nature. 2023 Sep;621(7980):804-812.
7. Bok S, Sun J, Greenblatt MB. Are osteoblasts multiple cell types? A new diversity in skeletal stem cells and their derivatives. J Bone Miner Res. 2024 Sep 26;39(10):1386-1392.
8. Xing W*, Feng H*, Jiang B, Gao B, Liu J, Xie Z, Zhang Y, Hu X, Sun J, Greenblatt MB, Zhou BO, Zou W. Itm2a expression marks periosteal skeletal stem cells that contribute to bone fracture healing. J Clin Invest. 2024 Sep 3;134(17).
9. Feng H*, Xing W*, Han Y*, Sun J, Kong M, Gao B, Yang Y, Yin Z, Chen X, Zhao Y, Bi Q, Zou W. Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification. J Clin Invest. 2020 Dec 1;130(12):6354-6365.
10. Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, Dai Q, Yang Y, Han A, Wei Z, Bi Q, Ji H, Kang T, Zou W. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019 May 1;129(5):1895-1909.
联系方式：
邮箱：junsun@ustc.edu.cn